CASP1

caspase 1

Details

HGNC: HGNC:1499
GeneCards: CASP1
NCBI: 834
Ensembl: ENSG00000137752
UniProt: P29466
OMIM: 147678
UCSC: uc021qpp.3
VEGA: OTTHUMG00000048072
ENA: U13697

Alias Symbols: ICE
Previous Symbols: IL1BC
Alias Names: "caspase-1", "interleukin 1, beta, convertase"
Previous Names: "caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)", "caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)", "caspase 1, apoptosis-related cysteine peptidase"

Associated Studies

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

2024 | Vu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)