CCL3

C-C motif chemokine ligand 3

Details

HGNC: HGNC:10627
GeneCards: CCL3
NCBI: 6348
Ensembl: ENSG00000277632
UniProt: P10147
OMIM: 182283
UCSC: uc032gca.3
VEGA: OTTHUMG00000188413
ENA: M23178
Alias Symbols: G0S19-1, LD78ALPHA, MIP-1-alpha, LD78, SCI
Previous Symbols: SCYA3
Alias Names: "macrophage inflammatory protein 1 alpha"
Previous Names: "small inducible cytokine A3 (homologous to mouse Mip-1a)", "chemokine (C-C motif) ligand 3"

Associated Studies

Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity

2025 | Beentjes et al

Phenotype: ME/CFS
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

2024 | Vu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome

2024 | Saito et al

Phenotype: Long COVID, ME/CFS, Post-exertional malaise (PEM)
Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study

2024 | Domingo et al

Phenotype: Long COVID, Long COVID - 2021 WHO criteria