CD74

CD74 molecule

Details

HGNC: HGNC:1697
GeneCards: CD74
NCBI: 972
Ensembl: ENSG00000019582
UniProt: P04233
OMIM: 142790
UCSC: uc003lse.4
VEGA: OTTHUMG00000163559
ENA: None
Alias Symbols: CLIP
Previous Symbols: DHLAG
Alias Names: "HLA-DR-gamma", "Ia-associated invariant chain", "gamma chain of class II antigens", "MHC HLA-DR gamma chain", "class II MHC-associated invariant chain peptide"
Previous Names: "CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)", "CD74 molecule, major histocompatibility complex, class II invariant chain"

Associated Studies

Multifaceted evolution focused on maximal exploitation of domain knowledge for the consensus inference of Gene Regulatory Networks

2025 | Segura-Ortiz et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing

2024 | Sun et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - Fukuda criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)