DFFA

DNA fragmentation factor subunit alpha

Details

HGNC: HGNC:2772
GeneCards: DFFA
NCBI: 1676
Ensembl: ENSG00000160049
UniProt: O00273
OMIM: 601882
UCSC: uc001arj.4
VEGA: OTTHUMG00000001909
ENA: AF087573
Alias Symbols: DFF-45, DFF45, ICAD, DFF1
Previous Symbols: None
Alias Names: "DNA fragmentation factor, 45 kD, alpha subunit"
Previous Names: "DNA fragmentation factor, 45 kD, alpha polypeptide", "DNA fragmentation factor, 45kDa, alpha polypeptide"

Associated Studies

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)