MAP2K1

mitogen-activated protein kinase kinase 1

Details

HGNC: HGNC:6840
GeneCards: MAP2K1
NCBI: 5604
Ensembl: ENSG00000169032
UniProt: Q02750
OMIM: 176872
UCSC: uc010bhq.4
VEGA: OTTHUMG00000133196
ENA: L11284

Alias Symbols: MEK1, MAPKK1, MKK1
Previous Symbols: PRKMK1
Alias Names: "MAPK/ERK kinase 1", "MAP kinase kinase 1", "dual specificity mitogen-activated protein kinase kinase 1"
Previous Names: None

Associated Studies

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Walitt et al

Phenotype: ME/CFS, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)