P4HB

prolyl 4-hydroxylase subunit beta

Details

HGNC: HGNC:8548
GeneCards: P4HB
NCBI: 5034
Ensembl: ENSG00000185624
UniProt: P07237
OMIM: 176790
UCSC: uc002kbn.2
VEGA: OTTHUMG00000150269
ENA: J02783
Alias Symbols: PDIA1, PROHB, DSI, GIT, PDI, PO4HB, P4Hbeta
Previous Symbols: PO4DB, ERBA2L
Alias Names: "protein disulfide isomerase-associated 1", "protein disulfide isomerase family A, member 1", "collagen prolyl 4-hydroxylase beta"
Previous Names: "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)", "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase-associated 1)", "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide", "prolyl 4-hydroxylase, beta polypeptide"

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz et al

Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
Extracellular vesicle proteomics uncovers energy metabolism, complement system, and endoplasmic reticulum stress response dysregulation postexercise in males with myalgic encephalomyelitis/chronic fatigue syndrome

2025 | Glass et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

2024 | Vu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
Dysregulation of extracellular vesicle protein cargo in female myalgic encephalomyelitis/chronic fatigue syndrome cases and sedentary controls in response to maximal exercise

2024 | Giloteaux et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Walitt et al

Phenotype: ME/CFS, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)