PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

Details

HGNC: HGNC:8975
GeneCards: PIK3CA
NCBI: 5290
Ensembl: ENSG00000121879
UniProt: P42336
OMIM: 171834
UCSC: uc003fjk.4
VEGA: OTTHUMG00000157311
ENA: None
Alias Symbols: PI3K
Previous Symbols: None
Alias Names: None
Previous Names: "phosphoinositide-3-kinase, catalytic, alpha polypeptide", "phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha"

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz et al

Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
Multifaceted evolution focused on maximal exploitation of domain knowledge for the consensus inference of Gene Regulatory Networks

2025 | Segura-Ortiz et al

Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Walitt et al

Phenotype: ME/CFS, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)