PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

Details

HGNC: HGNC:8979
GeneCards: PIK3R1
NCBI: 5295
Ensembl: ENSG00000145675
UniProt: P27986
OMIM: 171833
UCSC: uc003jva.4
VEGA: OTTHUMG00000131251
ENA: M61906
Alias Symbols: GRB1, p85-ALPHA, p85, p85alpha
Previous Symbols: None
Alias Names: "phosphoinositide-3-kinase regulatory subunit alpha", "growth factor receptor bound 1", "PI3 kinase-associated p85"
Previous Names: "phosphoinositide-3-kinase, regulatory subunit 1 (alpha)"

Associated Studies

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Immune exhaustion in ME/CFS and long COVID

2024 | Eaton-Fitch et al

Phenotype: ME/CFS, Post-exertional malaise (PEM)
Phenotype: Long COVID, Long COVID - CDC 2022 criteria
Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Walitt et al

Phenotype: ME/CFS, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)