PTPRC

protein tyrosine phosphatase receptor type C

Details

HGNC: HGNC:9666
GeneCards: PTPRC
NCBI: 5788
Ensembl: ENSG00000081237
UniProt: P08575
OMIM: 151460
UCSC: uc001gur.3
VEGA: OTTHUMG00000035702
ENA: Y00062

Alias Symbols: LCA, T200, GP180, LY5, B220, CD45R
Previous Symbols: CD45
Alias Names: "leukocyte-common antigen", "glycoprotein 180"
Previous Names: None

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz et al

Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

2024 | Vu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing

2024 | Sun et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - Fukuda criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome

2024 | Saito et al

Phenotype: Long COVID
Phenotype: Long COVID, ME/CFS, Post-exertional malaise (PEM)