SET

SET nuclear proto-oncogene

Details

HGNC: HGNC:10760
GeneCards: SET
NCBI: 6418
Ensembl: ENSG00000119335
UniProt: Q01105
OMIM: 600960
UCSC: uc004bvu.5
VEGA: OTTHUMG00000020755
ENA: M93651
Alias Symbols: PHAPII, 2PP2A, IPP2A2, TAF-IBETA, IGAAD, TAF-I
Previous Symbols: None
Alias Names: "protein phosphatase type 2A inhibitor", "Template-Activating Factor-I", "chromatin remodelling factor", "HLA-DR-associated protein II", "inhibitor of granzyme A-activated DNase"
Previous Names: "SET translocation (myeloid leukemia-associated)"

Associated Studies

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)