TGFBR1

transforming growth factor beta receptor 1

Details

HGNC: HGNC:11772
GeneCards: TGFBR1
NCBI: 7046
Ensembl: ENSG00000106799
UniProt: P36897
OMIM: 190181
UCSC: uc004azc.4
VEGA: OTTHUMG00000020353
ENA: None
Alias Symbols: ALK-5, ACVRLK4, ALK5, TBRI, TBR-i
Previous Symbols: MSSE, ESS1
Alias Names: "activin A receptor type II-like kinase, 53kDa"
Previous Names: "multiple self-healing squamous epithelioma", "transforming growth factor beta receptor I"

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz et al

Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)