TLR4

toll like receptor 4

Details

HGNC: HGNC:11850
GeneCards: TLR4
NCBI: 7099
Ensembl: ENSG00000136869
UniProt: O00206
OMIM: 603030
UCSC: uc004bjz.5
VEGA: OTTHUMG00000021046
ENA: U88880

Alias Symbols: hToll, CD284, TLR-4, ARMD10
Previous Symbols: None
Alias Names: None
Previous Names: "toll-like receptor 4"

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz et al

Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

2024 | Vu et al

Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)
Exercise-induced changes in gene expression do not mediate post exertional malaise in Gulf War illness

2023 | Boruch et al

Phenotype: Gulf war illness - Kansas Case Definition Criteria, Gulf War syndrome